School of Health Sciences & School of Nursing: Recent submissions
Now showing items 101-120 of 191
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In utero activation of fetal memory T cells alters host regulatory gene expression and affects HIV susceptibility
(Academic Press, 2012)The HIV-1 CCR5 co-receptor is a member of the chemokine receptor family of G-protein coupled receptors;for which a number of small molecule antagonists, such as vicriviroc (VCV), have been developed to inhibit HIV-1 R5-tropic ... -
In utero activation of fetal memory T cells alters host regulatory gene expression and affects HIV susceptibility
(Academic Press, 2012)In utero priming to malaria antigens renders cord blood mononuclear cells (CBMC) more susceptible to productive HIV infection in vitro in the absence of exogenous stimulation. This provides a unique model to better understand ... -
Reduced systemic bicyclo‐prostaglandin‐E2 and cyclooxygenase‐2 gene expression are associated with inefficient erythropoiesis and enhanced uptake of monocytic hemozoin in children with severe malarial anemia
(Wiley Subscription Services, Inc., 2012)In holoendemic Plasmodium falciparum transmission areas, severe malaria primarily occurs in children aged < 48 months and manifests as severe malarial anemia [SMA; hemoglobin (Hb) <6.0 g/dL]. Induction of high levels of ... -
Kenya and distance education: A model to advance graduate nursing
(Blackwell Publishing Asia Pty Ltd, 2012)Africa is faced with a myriad of challenges, such as HIV/AIDS, malaria, tuberculosis, and a variety of political and historical complications that have affected the educational system for advanced nursing practice. In ... -
The African Green Monkey (Cercopithecus aethiops) as a non-human primate model for infections with Cyclospora Cayetanensis
(The Kenya Veterinary Association, 2012)Clinical epidemiology and pathogenesis of Cyclospora species was studied in 64 wild-trapped Cercopithecus aethiops at the Institute of Primate Research, Nairobi, Kenya. The monkeys were screened for Cyclospora parasites ... -
Using podcasts to help students apply health informatics concepts: benefits and unintended consequences
(LWW, 2012)Despite requirements for robust health informatics education, a multitude of educators and policy analysts report that programs are not adequately preparing nurses to handle the bevy of technologies that will be a part of ... -
Projecting the long-term impact of school-or community-based mass-treatment interventions for control of Schistosoma infection
(Public Library of Science, 2012)Schistosomiasis remains a significant health burden in many areas of the world. Morbidity control, focused on limiting infection intensity through periodic delivery of anti-schistosomal medicines, is the thrust of current ... -
The role of personal opinions and experiences in compliance with mass drug administration for lymphatic filariasis elimination in Kenya
(Public Library of Science, 2012)The main strategy adopted for Lymphatic Filariasis (LF) elimination globally is annual mass drug administration (MDA) for 4 to 6 rounds. At least 65% of the population at risk should be treated in each round for LF elimination ... -
B-cell activity in children with malaria
(BioMed Central, 2012)Recent studies implicate deficiency of red blood cell (RBC) complement regulatory proteins (CR1 and CD55) in the pathogenesis of malarial anaemia. This study explored the involvement of B cell CD21, which has an analogous ... -
Effects of hygiene and sanitation interventions on reducing diarrhoea prevalence among children in resource constrained communities: case study of Turkana District, Kenya
(Springer US, 2012)Worldwide, lack of access to safe drinking water together with inadequate sanitation and hygiene is an overwhelming contributor to approximately 4 billion cases of illness annually. This study was set out to understand the ... -
Changing mother’s hygiene and sanitation practices in resource constrained communities: case study of Turkana District, Kenya
(Springer US, 2012)Lack of adequate sanitation, hygiene and safe portable water are serious global health problems that contribute to deaths of many children under the age of 5 years annually, mainly due to diarrhoeal diseases. This study ... -
Inequities in maternal and child health outcomes and interventions in Ghana
(BioMed Central, 2012)With the date for achieving the targets of the Millennium Development Goals (MDGs) approaching fast, there is a heightened concern about equity, as inequities hamper progress towards the MDGs. Equity-focused approaches ... -
Impact of malaria morbidity on gross domestic product in Uganda
(BioMed Central, 2012)The burden of malaria is a key challenge to both human and economic development in malaria endemic countries. The impact of malaria can be categorized from three dimensions, namely: health, social and economic. The objective ... -
Differentiating Schistosoma haematobium from related animal schistosomes by PCR amplifying inter-repeat sequences flanking newly selected repeated sequences
(The American Society of Tropical Medicine and Hygiene, 2012)In schistosomiasis elimination programs, successful discrimination of Schistosoma haematobium from the related animal Schistosoma parasites will be essential for accurate detection of human parasite transmission. Polymerase ... -
Bronchoscopy for Removal of Aspirated Tracheobronchial Foreign Bodies at Kenyatta National Hospital, in Kenya
(Association of Surgeons of East Africa/College of Surgeons of East Africa (COSECSA), 2013)This study was aimed at defining the presentation, morbidity and mortality following inhalation and subsequent removal of tracheobronchial foreign body using a rigid bronchoscope.This was a retrospective, cross-sectional ... -
Histologic and cytologic effects of vaginal estrogen in women with pelvic organ prolapse: a randomized controlled trial
(LWW, 2013)This study aimed to evaluate the histologic and cytologic effects of preoperative vaginal estrogen in women with atrophic vaginitis and pelvic organ prolapse.Forty-two women with atrophic vaginitis and stage greater than ... -
Moving from ideas to action-developing health financing systems towards universal coverage in Africa
(BioMed Central, 2012)Accelerating progress towards universal coverage in African countries calls for concrete actions that reinforce social health protection through establishment of sustainable health financing mechanisms. In order to explore ... -
National health financing policy in Eritrea: a survey of preliminary considerations
(BioMed Central, 2012)The 58th World Health Assembly and 56th WHO Regional Committee for Africa adopted resolutions urging Member States to ensure that health financing systems included a method for prepayment to foster financial risk sharing ... -
Birthweight in offspring of mothers with high prevalence of helminth and malaria infection in coastal Kenya
(The American Society of Tropical Medicine and Hygiene, 2013)Results of studies on the associations of maternal helminth infection and malaria-helminth co-infection on birth outcomes have been mixed. A group of 696 pregnant women from the Kwale district in Kenya were recruited and ... -
Monitoring malaria vector control interventions: effectiveness of five different adult mosquito sampling methods
(Oxford University Press, 2013)Long-term success of ongoing malaria control efforts based on mosquito bed nets (long-lasting insecticidal net) and indoor residual spraying is dependent on continuous monitoring of mosquito vectors, and thus on effective ...